Jean Chen Shih
- USC University Professor
- Holder of the Boyd P. and Elsie D. Welin Professorship in Molecular Pharmacology and Toxicology
- Professor of cell and neurobiology
- Professor, USC Alfred E. Mann School of Pharmacy and Pharmaceutical Sciences
- Member, USC Program in Neural, Informational and Behavioral Sciences
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Expertise Summary
Expert in cancer genetics and pathologies, tumor progression, clocks, and methods of growth
Expertise
- stress and its effects on brain chemistry
- molecular pharmacology and toxicology
- biochemistry and neurochemistry
- biochemical processes and aging
- molecular and biochemical bases of depression, memory, sleep, aggression, appetite and sexual behavior
- neurobiology
- enzyme regulation
- gene expression
- molecular biology
- pharmacogenetics - study of how genetic diversity afffects the efficacy and side effects of drugs
- serotonin receptors
- monoamine oxidase (MAO)
- genes and behavior
- gene knock-out mice
Languages
- Chinese
Additional Information
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- President of Society for Chinese American Neuroscientists (1994-96)
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- Co-founder of Cocensys, a biotechnology company to develop therapeutic
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- agents for disorders of the central nervous system
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- Shih and her collaborators are the first to have modeled the three-dimensional
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- structure of the brain enzyme monoamine oxidase (MAO)
- Two-time recipient of NIH Merit Award