Jean Chen Shih

USC University Professor

Holder of the Boyd P. and Elsie D. Welin Professorship in Molecular Pharmacology and Toxicology

Professor of cell and neurobiology

Professor, USC School of Pharmacy

Member, USC Program in Neural, Informational and Behavioral Sciences


  • stress and its effects on brain chemistry
  • molecular pharmacology and toxicology
  • biochemistry and neurochemistry
  • biochemical processes and aging
  • molecular and biochemical bases of
    depression, memory, sleep, aggression,
    appetite and sexual behavior
  • neurobiology
  • enzyme regulation
  • gene expression
  • molecular biology
  • pharmacogenetics – study of how
    genetic diversity afffects the efficacy
    and side effects of drugs
  • serotonin receptors
  • monoamine oxidase (MAO)
  • genes and behavior
  • gene knock-out mice

Additional Information

    • President of Society for Chinese American Neuroscientists (1994-96)


    • Co-founder of Cocensys, a biotechnology company to develop therapeutic


    • agents for disorders of the central nervous system


    • Shih and her collaborators are the first to have modeled the three-dimensional


    • structure of the brain enzyme monoamine oxidase (MAO)


    Two-time recipient of NIH Merit Award


  • Chinese

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